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Muscle pain that is felt throughout your whole body is most often caused by an infection, such as the flu Muscle pain also may be a side effect of certain medicines. Overview a muscle cramp is a sudden, unexpected tightening of one or more muscles Sometimes called a charley horse, a muscle cramp can be very painful Exercising or working hard, especially in heat, can lead to muscle cramps Some medicines and illnesses also might cause muscle cramps. What are statin side effects Muscle pain and damage one of the most common complaints of people taking statins is muscle pain You may feel this pain as a soreness, tiredness, or weakness in your muscles The pain can be a mild discomfort, or it can be serious enough to make it hard to do your daily activities. Tendinopathy is a term for any condition that affects a tendon Tendons are cords that attach muscle to bone Tendinopathy, which can cause pain and tenderness, is common It is often caused by overuse or repeated movement and tends to affect certain tendons in the arm or leg. A muscle strain is an injury to a muscle or a tendon — the fibrous tissue that connects muscles to bones Minor injuries may only overstretch a muscle or tendon, while more severe injuries may involve partial or complete tears in these tissues. Symptoms the muscle weakness associated with polymyositis involves the muscles closest to the trunk, such as those in your hips, thighs, shoulders, upper arms and neck The weakness affects both the left and right sides of your body, and tends to gradually worsen. Polymyalgia rheumatica is an inflammatory condition It causes joint and muscle pain and stiffness, mainly in the shoulders and hips Symptoms are most often worse in the morning Most people who get polymyalgia rheumatica are older than 65 Ataxia describes poor muscle control that causes clumsy movements It can affect walking and balance, hand coordination, speech and swallowing, and eye movements Ataxia usually results from damage to the part of the brain called the cerebellum or its connections Muscle weakness and a skin rash are hallmarks of dermatomyositis There's no cure, but treatments can relieve symptoms. These proteins work together to form strong connections between nerve cell signals and muscles.